Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28153791 | 1.00 | LMNA (0.62) | LMNAALOX15HSD17B10TSHRHIF1A | |
| Acrylic Acid SCHEMBL9592581 | 0.97 | — | — | |
| Acrylic Acid SCHEMBL7996084 | 0.92 | LMNA (0.53) | LMNAALOX15HSD17B10TSHRHIF1A | |
| Piperazine SCHEMBL28454920 | 0.89 | LMNA (0.50) | LMNAALOX15HSD17B10TSHRHIF1A | |
| Pyrrolidine SCHEMBL29060582 | 0.88 | LMNA (0.56) | LMNAALOX15HSD17B10TSHRGABRP | |
| Acrylic Acid SCHEMBL11118606 | 0.88 | LMNA (0.56) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Piperidine SCHEMBL4407343 | 0.86 | LMNA (0.53) | LMNAALOX15HSD17B10TSHRGABRP | |
| Acrylic Acid SCHEMBL672176 | 0.83 | — | — | |
| Acrylic Acid SCHEMBL673880 | 0.83 | — | — | |
| Acrylic Acid SCHEMBL28340495 | 0.81 | LMNA (0.62) | LMNAALOX15HSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4106913-A1 | COMPOSITIONS, METHODS AND SYSTEMS FOR SAMPLE PROCESSING | 10X Genomics, Inc. (US) | 2022-12-28 | — | — | EP | claimed |
| CN-115461143-A | Compositions, methods, and systems for sample processing | 10X基因组学有限公司 | 2022-12-09 | — | — | CN | claimed |
| EP-4499775-A1 | SYSTEMS AND METHODS IN WHICH POLYACRYLAMIDE GEL IS USED TO RESIST CORROSION OF A WELLHEAD COMPONENT IN A WELL CELLAR | Saudi Arabian Oil Company (SA) | 2025-02-05 | — | — | EP | disclosed |
| CN-118974203-A | System and method for using polyacrylamide gel to resist corrosion of wellhead components in square wells | 沙特阿拉伯石油公司 | 2024-11-15 | — | — | CN | disclosed |
| US-11988060-B2 | Systems and methods in which polyacrylamide gel is used to resist corrosion of a wellhead component in a well cellar | SAUDI ARABIAN OIL COMPANY (SA) | 2024-05-21 | — | — | US | disclosed |
| US-20230313628-A1 | SYSTEMS AND METHODS IN WHICH POLYACRYLAMIDE GEL IS USED TO RESIST CORROSION OF A WELLHEAD COMPONENT IN A WELL CELLAR | SAUDI ARABIAN OIL COMPANY (SA) | 2023-10-05 | — | — | US | disclosed |
| WO-2023192577-A1 | SYSTEMS AND METHODS IN WHICH POLYACRYLAMIDE GEL IS USED TO RESIST CORROSION OF A WELLHEAD COMPONENT IN A WELL CELLAR | SAUDI ARABIAN OIL COMPANY (SA) | 2023-10-05 | — | — | WO | disclosed |
| EP-4106913-A1 | COMPOSITIONS, METHODS AND SYSTEMS FOR SAMPLE PROCESSING | 10X Genomics, Inc. (US) | 2022-12-28 | — | — | EP | disclosed |
| US-20220397545-A1 | PHOTOCHEMICAL-BASED METHOD FOR ENZYME IMMOBILIZATION ON BIOSENSOR ELECTRODES | LAXMI THERAPEUTIC DEVICES INC (US) | 2022-12-15 | — | — | US | disclosed |
| CN-115461143-A | Compositions, methods, and systems for sample processing | 10X基因组学有限公司 | 2022-12-09 | — | — | CN | disclosed |