Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930240 | 1.00 | JMJD6 (0.41) | JMJD6CA12CA1CA2CA7 | |
| SCHEMBL24337507 | 0.85 | ALDH1A1 (0.42) | JMJD6CA12CA1CA2CA7 | |
| SCHEMBL31305819 | 0.82 | CA12 (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31297236 | 0.81 | HTT (0.41) | JMJD6CA12CA1CA2CA7 | |
| SCHEMBL20638918 | 0.81 | HTT (0.41) | JMJD6CA12CA1CA2CA7 | |
| SCHEMBL30562749 | 0.80 | HTT (0.40) | JMJD6CA12CA1CA2CA7 | |
| SCHEMBL25388657 | 0.80 | HTT (0.40) | JMJD6CA12CA1CA2CA7 | |
| SCHEMBL20639130 | 0.79 | KDM4E (0.50) | JMJD6CA12CA1CA2CA7 | |
| SCHEMBL22717775 | 0.78 | KMT2A (0.51) | JMJD6ALDH1A1NPC1MAPTTP53 | |
| SCHEMBL31049055 | 0.78 | KMT2A (0.51) | JMJD6ALDH1A1NPC1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |