SCHEMBL3000733

SCHEMBL3000733

CCOC(=O)C1C(S(=O)(=O)C(F)(F)F)C1S(=O)(=O)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.38
PTPN1 P18031 1/20 0.38
PPP1CC P36873 1/20 0.38
ALDH1A1 P00352 4/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 3/20 0.32
HSD17B10 Q99714 1/20 0.32
POLB P06746 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13822837 0.75 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10SOAT1
SCHEMBL12994228 0.72 ALDH1A1 (0.53) PPM1BPTPN1PPP1CCALDH1A1MAPT
SCHEMBL19874145 0.66 PPM1B (0.47) PPM1BPTPN1PPP1CCALDH1A1MAPT
SCHEMBL17165124 0.66 KMT2A (0.45) PPM1BPTPN1PPP1CCALDH1A1MAPT
SCHEMBL5944320 0.66 POLB (0.44) PPM1BPTPN1PPP1CCALDH1A1LMNA
SCHEMBL24318061 0.65 KDM4E (0.51) PPM1BPTPN1PPP1CCALDH1A1LMNA
SCHEMBL15015056 0.65 PPM1B (0.60) PPM1BPTPN1PPP1CCALDH1A1MAPT
SCHEMBL13449461 0.65 PPM1B (0.60) PPM1BPTPN1PPP1CCALDH1A1MAPT
SCHEMBL14874442 0.65 PPM1B (0.55) PPM1BPTPN1PPP1CCALDH1A1MAPT
SCHEMBL14874553 0.65 PPM1B (0.55) PPM1BPTPN1PPP1CCALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160102159-A1 Olefin Polymerization Catalyst and a Combined Catalyst Containing the Same PETROCHINA COMPANY LIMITED (CN) 2016-04-14 US claimed
US-8404789-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2013-03-26 US claimed
EP-2159232-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2012-11-21 EP claimed
US-20100184930-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2010-07-22 US claimed
US-20160102159-A1 Olefin Polymerization Catalyst and a Combined Catalyst Containing the Same PETROCHINA COMPANY LIMITED (CN) 2016-04-14 US disclosed