Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOL1 | O14791 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974875 | 1.00 | APOL1 (0.49) | APOL1 | |
| SCHEMBL30218288 | 0.90 | APOL1 (0.45) | APOL1 | |
| SCHEMBL30218358 | 0.88 | APOL1 (0.40) | APOL1 | |
| SCHEMBL31006363 | 0.85 | APOL1 (0.36) | APOL1 | |
| SCHEMBL22161369 | 0.84 | APOL1 (0.48) | APOL1 | |
| SCHEMBL22118318 | 0.84 | APOL1 (0.48) | APOL1 | |
| SCHEMBL30218333 | 0.84 | APOL1 (0.50) | APOL1 | |
| SCHEMBL30218341 | 0.84 | APOL1 (0.49) | APOL1 | |
| SCHEMBL28974842 | 0.82 | APOL1 (0.48) | APOL1 | |
| SCHEMBL22118432 | 0.80 | APOL1 (0.62) | APOL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867532-A | Inhibitors of APOL1 and uses thereof | 弗特克斯药品有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115867543-A | Solid forms of an APOL1 inhibitor and methods of use thereof | 弗特克斯药品有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115209894-A | Method for treating APOL-1 dependent focal segmental glomerulosclerosis | 弗特克斯药品有限公司 | 2022-10-18 | — | — | CN | disclosed |