SCHEMBL30007945

SCHEMBL30007945

CC(=O)Nc1cc(O)c(C(CCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C(C)C)=NO)cc1C

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 9/20 0.43
PPARA Q07869 9/20 0.43
PPARG P37231 6/20 0.43
FFAR1 O14842 9/20 0.39
MAPT P10636 1/20 0.37
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28868245 1.00 PPARD (0.43) PPARDPPARAPPARGFFAR1MAPT
SCHEMBL30008095 0.90 PPARD (0.45) PPARDPPARAPPARGFFAR1MAPT
SCHEMBL28868232 0.90 PPARD (0.45) PPARDPPARAPPARGFFAR1MAPT
SCHEMBL28868230 0.88 PPARD (0.45) PPARDPPARAPPARGFFAR1MAPT
SCHEMBL30007469 0.83 PPARD (0.53) PPARDPPARAPPARGFFAR1
SCHEMBL28868240 0.83 PPARD (0.53) PPARDPPARAPPARGFFAR1
SCHEMBL28868243 0.79 PPARD (0.49) PPARDPPARAPPARGFFAR1MAPT
SCHEMBL28868233 0.78 NPC1 (0.36) PPARDPPARAPPARGFFAR1MAPT
SCHEMBL30008188 0.78 NPC1 (0.36) PPARDPPARAPPARGFFAR1MAPT
SCHEMBL28868237 0.78 NPC1 (0.36) PPARDPPARAPPARGFFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115215856-B Preparation method of PPAR delta agonist Funadepad and intermediate thereof 沈阳药科大学 2024-10-11 CN claimed
CN-115215856-A Preparation method of PPAR delta agonist finadepa and intermediate thereof 沈阳药科大学 2022-10-21 CN claimed
CN-115215856-B Preparation method of PPAR delta agonist Funadepad and intermediate thereof 沈阳药科大学 2024-10-11 CN disclosed
CN-115215856-A Preparation method of PPAR delta agonist finadepa and intermediate thereof 沈阳药科大学 2022-10-21 CN disclosed