SCHEMBL30007966

SCHEMBL30007966

CC1(C)C=C(B2OC(C)(C)C(C)(C)O2)c2cccnc21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29060203 1.00 LPL (0.33) LPLLIPG
SCHEMBL25717145 0.73 LPL (0.41) LPLLIPG
SCHEMBL24097238 0.69 CYP19A1 (0.39) LPLLIPG
SCHEMBL971840 0.68 LPL (0.38) LPLLIPG
SCHEMBL29446647 0.68 LPL (0.38) LPLLIPG
SCHEMBL1535070 0.66 LPL (0.41) LPLLIPG
SCHEMBL31439383 0.65 LPL (0.36) LPLLIPG
SCHEMBL17746855 0.65 LPL (0.34) LPLLIPG
SCHEMBL17746831 0.65 LPL (0.39) LPLLIPG
SCHEMBL29060206 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022237825-A1 AZAARYL DERIVATIVE WITH EGFR INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF 上海和誉生物医药科技有限公司 2022-11-17 WO disclosed