Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 8/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24672761 | 1.00 | NT5E (0.42) | NT5EPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30008545 | 0.91 | NT5E (0.40) | NT5EPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24672048 | 0.91 | NT5E (0.40) | NT5EPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL27195210 | 0.84 | NT5E (0.42) | NT5EPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30008792 | 0.84 | NT5E (0.42) | NT5EPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30008458 | 0.84 | NT5E (0.54) | NT5EALDH1A1LMNAADORA2AADORA2B | |
| SCHEMBL24672760 | 0.84 | NT5E (0.54) | NT5EALDH1A1LMNAADORA2AADORA2B | |
| SCHEMBL26720613 | 0.80 | NT5E (0.39) | NT5EPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22104979 | 0.80 | NT5E (0.59) | NT5EPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30008079 | 0.80 | NT5E (0.59) | NT5EPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |