Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 16/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30008415 | 0.85 | NT5E (0.43) | NT5E | |
| SCHEMBL24672706 | 0.84 | NT5E (0.47) | NT5E | |
| SCHEMBL27195252 | 0.84 | NT5E (0.80) | NT5E | |
| SCHEMBL30008274 | 0.84 | NT5E (0.80) | NT5E | |
| SCHEMBL30008411 | 0.83 | NT5E (0.54) | NT5EADORA3 | |
| SCHEMBL27195120 | 0.83 | NT5E (0.54) | NT5EADORA3 | |
| SCHEMBL30008325 | 0.81 | NT5E (0.56) | NT5E | |
| SCHEMBL27195155 | 0.81 | NT5E (0.56) | NT5E | |
| SCHEMBL8820548 | 0.81 | ADORA1 (0.70) | ADORA1ADORA3ADORA2A | |
| SCHEMBL8820534 | 0.81 | ADORA1 (0.70) | ADORA1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642411-A | Small molecule CD73 antagonists and uses thereof | 西藏海思科制药有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |