Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820534 | 1.00 | ADORA1 (0.70) | ADORA1ADORA3ADORA2AADORA2BMEN1 | |
| SCHEMBL7627010 | 0.92 | ADORA3 (0.60) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL7627041 | 0.92 | ADORA3 (0.60) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8820273 | 0.91 | ADORA1 (0.73) | ADORA1ADORA3ADORA2AADORA2BMEN1 | |
| SCHEMBL8820255 | 0.91 | ADORA1 (0.73) | ADORA1ADORA3ADORA2AADORA2BMEN1 | |
| SCHEMBL5353431 | 0.89 | ADORA3 (0.67) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8820039 | 0.88 | ADORA1 (0.63) | ADORA1ADORA3ADORA2AADORA2BMEN1 | |
| SCHEMBL8820021 | 0.88 | ADORA1 (0.63) | ADORA1ADORA3ADORA2AADORA2BMEN1 | |
| SCHEMBL8908713 | 0.86 | ADORA1 (0.76) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8908726 | 0.86 | ADORA1 (0.76) | ADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430027-A | 2-chloro-N6 -substituted adenosines, their pharmaceutical compositions, and activity in treating ischemias | NOVO NORDISK A/S (DK) | 1995-07-04 | — | — | US | claimed |
| EP-0607367-A1 | NOVEL ADENOSINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-07-27 | — | — | EP | claimed |
| WO-1993023417-A1 | NOVEL ADENOSINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | claimed |
| WO-1997033590-A1 | A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS | NOVO NORDISK A/S (DK) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997033591-A1 | A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS | NOVO NORDISK A/S (DK) | 1997-09-18 | — | — | WO | disclosed |
| US-5430027-A | 2-chloro-N6 -substituted adenosines, their pharmaceutical compositions, and activity in treating ischemias | NOVO NORDISK A/S (DK) | 1995-07-04 | — | — | US | disclosed |
| EP-0607367-A1 | NOVEL ADENOSINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-07-27 | — | — | EP | disclosed |
| WO-1993023417-A1 | NOVEL ADENOSINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |