Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66472 | 1.00 | LOXL2 (0.54) | LOXL2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2773914 | 1.00 | LOXL2 (0.54) | LOXL2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL30506553 | 1.00 | LOXL2 (0.54) | LOXL2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2773919 | 1.00 | LOXL2 (0.54) | LOXL2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15134086 | 0.83 | TSHR (0.52) | LOXL2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL34953 | 0.83 | TSHR (0.70) | LOXL2ALDH1A1TSHRCYP4F2CYP4A11 | |
| SCHEMBL6596210 | 0.82 | CYP4F2 (0.51) | ALDH1A1TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL6596214 | 0.82 | CYP4F2 (0.51) | ALDH1A1TSHRCYP4F2CYP4A11RAB9A | |
| SCHEMBL2775628 | 0.82 | CA1 (0.55) | LOXL2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL13617864 | 0.82 | CA1 (0.55) | LOXL2ALDH1A1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059469-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AS AKT INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| EP-3704113-B1 | BRIDGED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-10-11 | — | — | EP | disclosed |
| EP-3704106-B1 | ALKENE COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-04-12 | — | — | EP | disclosed |
| EP-3377476-B1 | HYDROGEN ISOTOPE-ENRICHED ANALOGUES OF 1,2,4-OXADIAZOLE BENZOIC ACID COMPOUNDS, COMPOSITIONS AND USES THEREOF | PTC THERAPEUTICS INC (US) | 2022-10-26 | — | — | EP | disclosed |