Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 12/20 | 0.62 |
| ▸ | IKBKB | O14920 | 3/20 | 0.56 |
| ▸ | CHUK | O15111 | 3/20 | 0.56 |
| ▸ | NEK1 | Q96PY6 | 3/20 | 0.53 |
| ▸ | CIT | O14578 | 2/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
| ▸ | GRK5 | P34947 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009139 | 0.99 | JAK1 (0.61) | JAK1IKBKBCHUKNEK1CIT | |
| SCHEMBL30009807 | 0.97 | JAK1 (0.61) | JAK1IKBKBCHUKNEK1CIT | |
| SCHEMBL30009063 | 0.91 | ROCK2 (0.54) | JAK1IKBKBCHUKNEK1CIT | |
| SCHEMBL30009207 | 0.89 | JAK1 (0.53) | JAK1IKBKBCHUKNEK1CIT | |
| SCHEMBL30008764 | 0.89 | JAK1 (0.63) | JAK1IKBKBCHUKNEK1CIT | |
| SCHEMBL30009468 | 0.89 | JAK1 (0.63) | JAK1IKBKBCHUKNEK1PRKAA1 | |
| SCHEMBL30009811 | 0.89 | JAK1 (0.63) | JAK1IKBKBCHUKNEK1CIT | |
| SCHEMBL30009818 | 0.87 | JAK1 (0.52) | JAK1IKBKBCHUKNEK1CIT | |
| SCHEMBL30009454 | 0.84 | JAK1 (0.68) | JAK1IKBKBCHUKJAK2JAK3 | |
| SCHEMBL857458 | 0.82 | IKBKB (0.63) | IKBKBCHUKNEK1CITDAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | JAK1 83/4885IKBKB 294/4885CHUK 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.