Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.64 |
| ▸ | JAK1 | P23458 | 1/20 | 0.61 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.56 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.56 |
| ▸ | CHUK | O15111 | 2/20 | 0.53 |
| ▸ | INSR | P06213 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4792087 | 0.81 | NEK1 (0.62) | NEK1MAPK8CAMKK2CHUKINSR | |
| SCHEMBL31289890 | 0.81 | NPC1 (0.57) | JAK1NPC1RAB9APRKCQPRKCD | |
| SCHEMBL4830288 | 0.78 | NEK1 (0.58) | NEK1MAPK8CHUKTBK1PRKCQ | |
| SCHEMBL858754 | 0.77 | IKBKB (0.57) | NEK1MAPK8CHUKPRKCQPRKAA1 | |
| SCHEMBL30009109 | 0.77 | IKBKB (0.57) | NEK1MAPK8CHUKPRKCQPRKAA1 | |
| SCHEMBL30356217 | 0.76 | JAK1 (1.00) | JAK1 | |
| SCHEMBL20919169 | 0.76 | JAK1 (1.00) | JAK1 | |
| SCHEMBL5395486 | 0.76 | CCNK (0.60) | NEK1MAPK8CHUKPRKCQPRKAA1 | |
| SCHEMBL1717834 | 0.73 | NEK1 (0.53) | NEK1MAPK8CAMKK2CHUKTBK1 | |
| SCHEMBL4873430 | 0.73 | IKBKB (0.60) | NEK1JAK1MAPK8CHUKPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | NEK1 178/4885JAK1 83/4885MAPK8 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.