Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 9/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 6/20 | 0.32 |
| ▸ | MAOB | P27338 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994793 | 0.91 | HTR2A (0.31) | HTR2AKDM1ARCOR1 | |
| SCHEMBL2993024 | 0.81 | HTR2A (0.35) | HTR2AKDM1ARCOR1MAOAMAOB | |
| SCHEMBL3003257 | 0.77 | HTR2C (0.40) | HTR2A | |
| SCHEMBL2995990 | 0.76 | HTR2C (0.36) | HTR2AKDM1ARCOR1 | |
| SCHEMBL10865321 | 0.75 | HTR2A (0.37) | HTR2AKDM1ARCOR1MAOAMAOB | |
| SCHEMBL10316488 | 0.72 | HTR2A (0.35) | HTR2AKDM1ARCOR1MAOAMAOB | |
| SCHEMBL2988144 | 0.66 | HTR2A (0.31) | HTR2AKDM1ARCOR1 | |
| SCHEMBL13377608 | 0.64 | IDO1 (0.36) | HTR2AMAOAMAOB | |
| SCHEMBL11311503 | 0.62 | AKR1B1 (0.39) | HTR2AKDM1AMAOAMAOB | |
| SCHEMBL10389798 | 0.59 | GAA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |