Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 8/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988144 | 0.91 | HTR2A (0.31) | HTR2AKDM1ARCOR1CYP3A4MEN1 | |
| SCHEMBL2990097 | 0.81 | HTR2A (0.35) | HTR2AKDM1ARCOR1CYP3A4MEN1 | |
| SCHEMBL2993915 | 0.77 | CYP3A4 (0.38) | HTR2ACYP3A4MEN1CYP2D6ALOX15 | |
| SCHEMBL2999466 | 0.76 | HTR2C (0.33) | HTR2AKDM1ARCOR1CYP3A4MEN1 | |
| SCHEMBL10865321 | 0.75 | HTR2A (0.37) | HTR2AKDM1ARCOR1MAOAMAOB | |
| SCHEMBL3000893 | 0.72 | HTR2A (0.35) | HTR2AKDM1ARCOR1MAOAMAOB | |
| SCHEMBL2994793 | 0.66 | HTR2A (0.31) | HTR2AKDM1ARCOR1 | |
| SCHEMBL11311503 | 0.62 | AKR1B1 (0.39) | HTR2AKDM1ACYP3A4MEN1ALOX15 | |
| SCHEMBL18289375 | 0.60 | OPRM1 (0.31) | — | |
| SCHEMBL977743 | 0.60 | HTR2A (0.33) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |