Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5073539 | 0.89 | ABCB11 (0.30) | ALDH1A1HSD17B10 | |
| SCHEMBL897853 | 0.66 | CDC25B (0.38) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL2796799 | 0.66 | ABCG2 (0.37) | — | |
| SCHEMBL21801601 | 0.63 | SETD7 (0.33) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL225315 | 0.61 | MEN1 (0.41) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL12672548 | 0.61 | MEN1 (0.41) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL29726351 | 0.61 | MEN1 (0.41) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL17936809 | 0.61 | MEN1 (0.46) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL9181176 | 0.61 | PTPRC (0.44) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL17261614 | 0.60 | MEN1 (0.42) | KDM4EMEN1ALDH1A1LMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237813-A1 | COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-17 | — | — | WO | disclosed |