Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302776 | 1.00 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EHSD17B10MAP2K1 | |
| SCHEMBL12428146 | 0.88 | HSD17B10 (0.74) | ALDH1A1LMNAKDM4EHSD17B10MAP2K1 | |
| SCHEMBL30533222 | 0.85 | MAP2K1 (0.70) | ALDH1A1LMNAKDM4EHSD17B10MAP2K1 | |
| SCHEMBL14739587 | 0.85 | MAP2K1 (0.70) | ALDH1A1LMNAKDM4EHSD17B10MAP2K1 | |
| SCHEMBL29403077 | 0.84 | ALDH1A1 (0.73) | ALDH1A1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL14739175 | 0.84 | KDM4E (0.64) | ALDH1A1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL14740027 | 0.84 | ALDH1A1 (0.73) | ALDH1A1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL30116222 | 0.84 | KDM4E (0.64) | ALDH1A1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL2302082 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EHSD17B10MEN1 | |
| SCHEMBL29403397 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EHSD17B10MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4340835-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIOVASCULAR DISEASE | METANOIA BIO INC. (US) | 2024-03-27 | — | — | EP | disclosed |
| EP-4340896-A1 | METHODS AND COMPOSITIONS FOR TREATING OCULAR NEOVASCULAR DISEASE | METANOIA BIO INC. (US) | 2024-03-27 | — | — | EP | disclosed |
| EP-4340836-A1 | METHODS AND COMPOSITIONS FOR TREATING NEUROLOGICAL CONDITIONS | METANOIA BIO INC. (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-116615241-A | Methods and compositions for diabetes treatment and beta cell regeneration | 加利福尼亚大学董事会 | 2023-08-18 | — | — | CN | disclosed |
| WO-2022245711-A1 | METHODS AND COMPOSITIONS FOR TREATING NEUROLOGICAL CONDITIONS | METANOIA BIO INC. (US) | 2022-11-24 | — | — | WO | disclosed |
| WO-2022245697-A1 | METHODS AND COMPOSITIONS FOR TREATING OCULAR NEOVASCULAR DISEASE | METANOIA BIO INC. (US) | 2022-11-24 | — | — | WO | disclosed |
| WO-2022245702-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIOVASCULAR DISEASE | METANOIA BIO INC. (US) | 2022-11-24 | — | — | WO | disclosed |