SCHEMBL30009271

SCHEMBL30009271

COC(=O)NS(=O)(=O)c1ccccc1F

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 12/20 0.50
TSHR P16473 1/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.45
GBA1 P04062 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28282283 0.82 KAT6A (0.53) KAT6ATSHRMEN1KMT2AALDH1A1
SCHEMBL13329854 0.81 CA1 (0.50) KAT6AALDH1A1
SCHEMBL9037138 0.81 PKM (0.41) KAT6AKMT2A
SCHEMBL27176171 0.80 KAT6A (0.58) KAT6ATSHRMEN1KMT2AALDH1A1
SCHEMBL26112980 0.80 KCNH2 (0.53) KAT6A
SCHEMBL3335057 0.79 POLB (0.54) TSHRALDH1A1MAPT
SCHEMBL7552123 0.79 KAT6A (0.52) KAT6ATSHR
SCHEMBL13026210 0.79 ITGAV (0.42) MEN1KMT2AALDH1A1MAPT
SCHEMBL9212071 0.79 MEN1 (0.52) KAT6AMEN1KMT2AALDH1A1
SCHEMBL30591430 0.79 MEN1 (0.52) KAT6AMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4341246-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2024-03-27 EP disclosed
WO-2022245627-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-11-24 WO disclosed