SCHEMBL30009288

SCHEMBL30009288

N#CCC(=O)NC1CCN(c2ccnc3[nH]ccc23)CC1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AKT2 P31751 3/20 0.57
PBK Q96KB5 2/20 0.51
JAK3 P52333 11/20 0.48
JAK2 O60674 7/20 0.48
JAK1 P23458 5/20 0.48
GSK3B P49841 1/20 0.47
ATR Q13535 2/20 0.46
ATRIP Q8WXE1 2/20 0.46
AKT1 P31749 2/20 0.45
NUDT1 P36639 1/20 0.44
TYK2 P29597 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12613782 0.83 JAK1 (0.45) JAK3JAK2JAK1TYK2
SCHEMBL12612756 0.82 DRD2 (0.46) JAK3JAK2JAK1TYK2
SCHEMBL12612259 0.82 JAK3 (0.45) JAK3JAK2JAK1TYK2
SCHEMBL12612623 0.81 JAK1 (0.46) JAK3JAK2JAK1TYK2
SCHEMBL30009396 0.81 AKT1 (0.54) AKT2PBKJAK3JAK2JAK1
SCHEMBL15618964 0.81 JAK3 (0.42) PBKJAK3JAK2JAK1TYK2
SCHEMBL30356239 0.80 JAK1 (0.67) JAK1
SCHEMBL20918736 0.80 JAK1 (0.67) JAK1
SCHEMBL12612525 0.79 JAK3 (0.46) JAK3JAK2JAK1TYK2
SCHEMBL12613606 0.78 JAK3 (0.49) JAK3JAK2JAK1TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor HK INNO.N CORPORATION (KR) 2022-12-13 US claimed
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor HK INNO.N CORPORATION (KR) 2022-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor MAP3K20, MAP3K15, MAP3K1 AKT2 208/4885PBK 1017/4885JAK3 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.