Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 12/20 | 0.59 |
| ▸ | IKBKB | O14920 | 1/20 | 0.54 |
| ▸ | CHUK | O15111 | 1/20 | 0.54 |
| ▸ | KIT | P10721 | 5/20 | 0.53 |
| ▸ | JAK2 | O60674 | 8/20 | 0.52 |
| ▸ | JAK3 | P52333 | 4/20 | 0.52 |
| ▸ | CIT | O14578 | 2/20 | 0.51 |
| ▸ | TYK2 | P29597 | 2/20 | 0.50 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | MARK3 | P27448 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30008756 | 0.86 | IKBKB (0.56) | JAK1IKBKBCHUKKITJAK2 | |
| SCHEMBL30009793 | 0.86 | KIT (0.71) | JAK1IKBKBCHUKKITJAK2 | |
| SCHEMBL30009538 | 0.83 | KIT (0.69) | JAK1IKBKBCHUKKITJAK2 | |
| SCHEMBL30009783 | 0.83 | KIT (0.47) | JAK1IKBKBCHUKKITJAK2 | |
| SCHEMBL30009580 | 0.83 | JAK1 (0.59) | JAK1IKBKBCHUKKITJAK2 | |
| SCHEMBL30009248 | 0.83 | IKBKB (0.61) | JAK1IKBKBCHUKKITJAK2 | |
| SCHEMBL30009155 | 0.82 | IKBKB (0.63) | JAK1IKBKBCHUKCITROCK1 | |
| SCHEMBL30009244 | 0.81 | IKBKB (0.55) | JAK1IKBKBCHUKKITJAK2 | |
| SCHEMBL24805256 | 0.79 | IKBKB (0.70) | IKBKBCHUKKITJAK2JAK3 | |
| SCHEMBL30009334 | 0.75 | IKBKB (0.60) | JAK1IKBKBCHUKKITJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | JAK1 83/4885IKBKB 294/4885CHUK 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.