SCHEMBL30009302

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14493878	0.85	CCNT1 (0.50)	JAK1CDK9CCNT1CHEK1MAP4K4
	SCHEMBL30009520	0.82	JAK1 (0.62)	JAK1CHEK1MAP4K4PIM1PRKACA
	SCHEMBL14493885	0.80	JAK1 (0.57)	JAK1CDK9CCNT1JAK3
	SCHEMBL10125393	0.80	JAK1 (0.64)	JAK1CDK9CCNT1CHEK1MAP4K4
	SCHEMBL30009343	0.80	JAK1 (0.48)	JAK1CDK9CCNT1CHEK1MAP4K4
	SCHEMBL3602461	0.80	JAK1 (0.65)	JAK1CDK9CCNT1
	SCHEMBL14420789	0.79	JAK1 (0.50)	JAK1CDK9CCNT1
	SCHEMBL23485739	0.78	JAK1 (0.84)	JAK1
	SCHEMBL29430994	0.77	JAK1 (0.47)	JAK1CDK9CCNT1CHEK1MAP4K4
	SCHEMBL27819451	0.75	HTR1A (0.46)	JAK1CDK9CCNT1AURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.