Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 10/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 8/20 | 0.38 |
| ▸ | TYK2 | P29597 | 5/20 | 0.38 |
| ▸ | JAK3 | P52333 | 5/20 | 0.38 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20930667 | 0.80 | JAK1 (0.73) | JAK1 | |
| SCHEMBL30009215 | 0.77 | JAK1 (0.44) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL4054113 | 0.70 | JAK2 (0.52) | JAK1NUDT1PDE2APDE3AJAK2 | |
| SCHEMBL30009023 | 0.69 | ALDH1A1 (0.43) | JAK1PDE2APDE3AJAK2 | |
| SCHEMBL30009611 | 0.67 | JAK1 (0.64) | JAK1JAK2TYK2JAK3ROCK2 | |
| SCHEMBL30009345 | 0.65 | JAK1 (0.60) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL21821940 | 0.65 | PRKCI (0.44) | JAK1NUDT1PDE2APDE3AJAK2 | |
| SCHEMBL30009854 | 0.65 | GAA (0.45) | JAK1PDE2APDE3AJAK2TYK2 | |
| SCHEMBL29431228 | 0.65 | JAK1 (0.66) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL29431229 | 0.65 | JAK1 (0.66) | JAK1JAK2TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | JAK1 83/4885NUDT1 3177/4885AR 2124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.