Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 4/20 | 1.00 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 1.00 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | PRKCI | P41743 | 2/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.51 |
| ▸ | PRKACA | P17612 | 3/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | CHUK | O15111 | 2/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | JAK3 | P52333 | 2/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839635 | 1.00 | CCNK (1.00) | CCNKCDK12JAK1PRKCIMAP4K4 | |
| SCHEMBL20849907 | 0.90 | CCNK (1.00) | CCNKCDK12JAK1PRKCIJAK2 | |
| SCHEMBL20849889 | 0.88 | CCNK (0.79) | CCNKCDK12JAK1PRKCIMAP4K4 | |
| SCHEMBL20839751 | 0.86 | CCNK (1.00) | CCNKCDK12JAK1ROCK1CDC7 | |
| SCHEMBL30574749 | 0.86 | CCNK (0.75) | CCNKCDK12JAK1PRKCIMAP4K4 | |
| SCHEMBL719570 | 0.83 | CCNK (0.71) | CCNKCDK12MAP4K4PRKACACLK4 | |
| SCHEMBL20849913 | 0.82 | CCNK (1.00) | CCNKCDK12JAK1PRKCIMAP4K4 | |
| SCHEMBL25351686 | 0.79 | CCNK (0.64) | CCNKCDK12JAK1KDRALK | |
| SCHEMBL99234 | 0.78 | GRM4 (0.65) | CCNKCDK12JAK1PRKCIMAP4K4 | |
| SCHEMBL30009527 | 0.78 | GRM4 (0.65) | CCNKCDK12JAK1PRKCIMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | CCNK 820/4885CDK12 525/4885JAK1 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.