Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 15/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217696 | 1.00 | CFD (0.45) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL21438324 | 0.93 | CFD (0.45) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL30010416 | 0.91 | CFD (0.45) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23217566 | 0.91 | CFD (0.45) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL21437877 | 0.90 | CFD (0.42) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL29672927 | 0.89 | CFD (0.57) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23217657 | 0.89 | CFD (0.57) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23217706 | 0.88 | CFD (0.53) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL30010049 | 0.88 | CFD (0.53) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL25883804 | 0.88 | CFD (0.40) | CFDPLGPLAUF11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041717-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |