SCHEMBL30009709

SCHEMBL30009709

CC(NC(=O)OC(C)(C)C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.48
MDM2 Q00987 1/20 0.48
MDM4 O15151 2/20 0.47
TP53 P04637 2/20 0.47
KMT2A Q03164 2/20 0.45
IDO1 P14902 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20299866 1.00 CASP3 (0.48) CASP3MDM2MDM4TP53KMT2A
SCHEMBL20299865 1.00 CASP3 (0.48) CASP3MDM2MDM4TP53KMT2A
SCHEMBL31688935 1.00 CASP3 (0.48) CASP3MDM2MDM4TP53KMT2A
SCHEMBL30229458 1.00 CASP3 (0.48) CASP3MDM2MDM4TP53KMT2A
SCHEMBL30229769 1.00 CASP3 (0.48) CASP3MDM2MDM4TP53KMT2A
SCHEMBL24899351 1.00 CASP3 (0.48) CASP3MDM2MDM4TP53KMT2A
SCHEMBL31440994 0.92 CASP3 (0.54) CASP3MDM2MDM4TP53KMT2A
SCHEMBL26666635 0.92 CASP3 (0.54) CASP3MDM2MDM4TP53KMT2A
SCHEMBL21890680 0.91 CASP3 (0.46) CASP3MDM2MDM4TP53KMT2A
SCHEMBL3018041 0.91 CASP3 (0.46) CASP3MDM2MDM4TP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110300578-B Compounds for the treatment of respiratory diseases in cattle or pigs 英特维特国际股份有限公司 2022-12-13 CN disclosed