Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217889 | 1.00 | FGFR1 (0.44) | FGFR1RHEBTTRNOTUMPLA2G4A | |
| SCHEMBL30010282 | 0.85 | FGFR1 (0.47) | FGFR1NOTUMKDM4EP2RX3P2RX2 | |
| SCHEMBL21439171 | 0.85 | FGFR1 (0.47) | FGFR1NOTUMKDM4EP2RX3P2RX2 | |
| SCHEMBL732887 | 0.78 | CA12 (0.45) | FGFR1TTRNOTUMKDM4EPKM | |
| SCHEMBL29856013 | 0.76 | TTR (0.44) | RHEBTTRKDM4E | |
| SCHEMBL19100569 | 0.76 | TTR (0.44) | RHEBTTRKDM4E | |
| SCHEMBL21439140 | 0.76 | RHEB (0.35) | FGFR1RHEBNOTUMPLA2G4AHDAC3 | |
| SCHEMBL21439305 | 0.75 | RHEB (0.67) | RHEBNOTUMHDAC3HDAC4HDAC1 | |
| SCHEMBL24950460 | 0.73 | FGFR1 (0.55) | FGFR1NOTUMPLA2G4AHDAC3HDAC4 | |
| SCHEMBL30201454 | 0.73 | FGFR1 (0.55) | FGFR1NOTUMPLA2G4AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041717-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |