Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 2/20 | 0.42 |
| ▸ | TPMT | P51580 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19100569 | 1.00 | TTR (0.44) | TTRRHEBTPMTKDM4ETHRA | |
| SCHEMBL20610528 | 0.85 | ALDH1A1 (0.41) | RHEBKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL348258 | 0.83 | KDM4E (0.48) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29855962 | 0.83 | KDM4E (0.48) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL26581107 | 0.81 | SLC22A12 (0.40) | TTRTPMTKDM4ETUBB4ATUBB | |
| SCHEMBL16899563 | 0.80 | RHEB (0.48) | TTRRHEBTPMTKDM4ETUBB4A | |
| SCHEMBL21438922 | 0.80 | HCAR3 (0.41) | TTRRHEBTPMTKDM4ETHRA | |
| SCHEMBL23809345 | 0.78 | SLC22A12 (0.42) | KDM4ETHRATHRBTUBB4ATUBB | |
| SCHEMBL19475816 | 0.77 | MAP3K5 (0.44) | KDM4EKDM2BKDM4CHCAR3ALDH1A1 | |
| SCHEMBL23217889 | 0.76 | FGFR1 (0.44) | TTRRHEBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022166916-A1 | SUBSTITUTED HETEROARYL DERIVATIVE, AND COMPOSITION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2022-08-11 | — | — | WO | disclosed |