SCHEMBL30009866

SCHEMBL30009866

c1cc(CN2CCN(c3ccnc4[nH]ccc34)CC2)sn1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
JAK1 P23458 1/20 0.59
AKT2 P31751 6/20 0.52
NUDT1 P36639 5/20 0.46
PBK Q96KB5 2/20 0.46
GSK3B P49841 2/20 0.45
AKT1 P31749 2/20 0.43
METTL3 Q86U44 1/20 0.42
PRKCI P41743 1/20 0.41
DRD4 P21917 1/20 0.40
HTR1A P08908 1/20 0.39
HTR2A P28223 1/20 0.39
HTR7 P34969 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2800151 0.79 DRD2 (0.63) JAK1AKT2NUDT1PBKGSK3B
SCHEMBL30356007 0.75 JAK1 (1.00) JAK1
SCHEMBL12605440 0.74 AKT2 (0.70) AKT2NUDT1PBKGSK3BPRKCI
SCHEMBL18440877 0.74 AKT2 (0.65) AKT2NUDT1PBKGSK3BAKT1
SCHEMBL12605438 0.74 AKT2 (0.65) AKT2NUDT1PBKGSK3BPRKCI
SCHEMBL12605530 0.73 AKT2 (0.68) AKT2NUDT1PBKGSK3BPRKCI
SCHEMBL2799562 0.72 AKT2 (0.67) AKT2NUDT1PBKGSK3B
SCHEMBL30040884 0.72 HRH4 (0.52) AKT2NUDT1AKT1DRD4HTR1A
SCHEMBL25505716 0.72 HRH4 (0.52) AKT2NUDT1AKT1DRD4HTR1A
Hydrochloric Acid SCHEMBL2800609 0.71 AKT2 (0.65) AKT2NUDT1PBKGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor HK INNO.N CORPORATION (KR) 2022-12-13 US claimed
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor HK INNO.N CORPORATION (KR) 2022-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor MAP3K20, MAP3K15, MAP3K1 JAK1 83/4885AKT2 208/4885NUDT1 3177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.