Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 5/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217821 | 1.00 | CFD (0.41) | CFDDPP4PTPN1PDCD1CD274 | |
| SCHEMBL21437288 | 0.91 | CFD (0.43) | CFDDPP4FFAR1 | |
| SCHEMBL21438052 | 0.91 | CFD (0.43) | CFDDPP4MEN1KMT2APOLB | |
| SCHEMBL29672953 | 0.90 | CFD (0.49) | CFDPDCD1CD274FFAR1 | |
| SCHEMBL23217609 | 0.90 | CFD (0.49) | CFDPDCD1CD274FFAR1 | |
| SCHEMBL21438528 | 0.90 | CFD (0.46) | CFDDPP4MEN1KMT2APOLB | |
| SCHEMBL21437785 | 0.90 | CFD (0.49) | CFDDPP4PTPN1MEN1KMT2A | |
| SCHEMBL21438711 | 0.88 | CFD (0.44) | CFDPTPN1MTNR1AFFAR1 | |
| SCHEMBL21438862 | 0.87 | CFD (0.50) | CFDDPP4PTPN1PDCD1CD274 | |
| SCHEMBL21437941 | 0.86 | CFD (0.43) | CFDDPP4MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041717-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |