SCHEMBL30010895

SCHEMBL30010895

N[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 3/20 0.59
▸ NPY2R P49146 3/20 0.59
▸ NPY4R P50391 3/20 0.59
▸ ACE P12821 1/20 0.59
▸ IL1RN P18510 1/20 0.59
▸ ERAP2 Q6P179 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30011136 1.00 NPY1R (0.59) NPY1RNPY2RNPY4RACEIL1RN
SCHEMBL30010717 1.00 NPY1R (0.59) NPY1RNPY2RNPY4RACEIL1RN
SCHEMBL30010546 1.00 NPY1R (0.59) NPY1RNPY2RNPY4RACEIL1RN
SCHEMBL30010227 1.00 NPY1R (0.59) NPY1RNPY2RNPY4RACEIL1RN
SCHEMBL30010869 1.00 NPY1R (0.59) NPY1RNPY2RNPY4RACEIL1RN
SCHEMBL30011186 0.97 ACE (0.63) NPY1RNPY2RNPY4RACEIL1RN
SCHEMBL30010361 0.97 ACE (0.63) NPY1RNPY2RNPY4RACEIL1RN
SCHEMBL30010852 0.97 ACE (0.63) NPY1RNPY2RNPY4RACEIL1RN
SCHEMBL30010228 0.97 ACE (0.63) NPY1RNPY2RNPY4RACEIL1RN
SCHEMBL30011238 0.97 ACE (0.63) NPY1RNPY2RNPY4RACEIL1RN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345411-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2025-11-13 — — US disclosed
US-20250345410-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2025-11-13 — — US disclosed
US-12390520-B2 Vaccination in newborns and infants Cure Vac SE (DE) 2025-08-19 — — US disclosed
US-20240390478-A1 VACCINATION IN ELDERLY PATIENTS CureVac SE (DE) 2024-11-28 — — US disclosed
US-12036277-B2 Vaccination with mRNA-coded antigens CureVac SE (DE) 2024-07-16 — — US disclosed
US-20240197857-A1 VACCINATION WITH mRNA-CODED ANTIGENS CureVac SE (DE) 2024-06-20 — — US disclosed
US-11975064-B2 Vaccination with mRNA-coded antigens CureVac SE (DE) 2024-05-07 — — US disclosed
US-20230302146-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CureVac SE (DE) 2023-09-28 — — US disclosed
US-20230285594-A1 COMPLEXATION OF NUCLEIC ACIDS WITH DISULFIDE-CROSSLINKED CATIONIC COMPONENTS FOR TRANSFECTION AND IMMUNOSTIMULATION CureVac SE (DE) 2023-09-14 — — US disclosed
US-20230233662-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2023-07-27 — — US disclosed
US-11672856-B2 Vaccination in newborns and infants CureVac SE (DE) 2023-06-13 — — US disclosed
US-11478552-B2 Hybrid carriers for nucleic acid cargo CUREVAC AG (DE) 2022-10-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11478552-B2 Hybrid carriers for nucleic acid cargo HNRNPH1, HNRNPH3, SNRPE NPY1R 3867/4885NPY2R 3332/4885NPY4R 2857/4885
US-20250345410-A1 VACCINATION IN NEWBORNS AND INFANTS HLA-DRB1, TLR3, TLR9 NPY1R 2188/4885NPY2R 2305/4885NPY4R 2247/4885
US-20230302146-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO HNRNPH1, HNRNPH3, SNRPE NPY1R 3867/4885NPY2R 3332/4885NPY4R 2857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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