Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 11/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27246292 | 1.00 | MGLL (0.40) | MGLLNR1H2PTGDR2NR1H3TRPV4 | |
| SCHEMBL30012545 | 0.89 | MGLL (0.40) | MGLLNR1H2NR1H3GPBAR1 | |
| SCHEMBL30013112 | 0.87 | NR1H2 (0.41) | MGLLNR1H2NR1H3 | |
| SCHEMBL27246348 | 0.87 | NR1H2 (0.41) | MGLLNR1H2NR1H3 | |
| SCHEMBL30012263 | 0.85 | MGLL (0.42) | MGLLHRH3 | |
| SCHEMBL27246270 | 0.85 | MGLL (0.42) | MGLLHRH3 | |
| SCHEMBL30011692 | 0.83 | MGLL (0.39) | MGLLTRPV4HRH3 | |
| SCHEMBL27149525 | 0.83 | MGLL (0.39) | MGLLTRPV4HRH3 | |
| SCHEMBL25326309 | 0.82 | MGLL (0.43) | MGLLPTGDR2 | |
| SCHEMBL25326670 | 0.82 | MGLL (0.43) | MGLLPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326714-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-02-28 | — | — | EP | claimed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | claimed |
| WO-2022223750-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-10-27 | — | — | WO | claimed |
| EP-4326714-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-02-28 | — | — | EP | disclosed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |
| WO-2022223750-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-10-27 | — | — | WO | disclosed |