SCHEMBL30012201

SCHEMBL30012201

Nc1ccc(N2c3ccccc3Sc3ccccc32)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.54
NOX1 Q9Y5S8 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
ADRA2A P08913 2/20 0.51
ADRA2B P18089 2/20 0.51
ADRA2C P18825 2/20 0.51
CHRM3 P20309 1/20 0.51
SLC6A2 P23975 1/20 0.51
HTR2C P28335 1/20 0.51
SLC6A4 P31645 1/20 0.51
DRD3 P35462 1/20 0.51
HTR2B P41595 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MAOA P21397 1/20 0.47
BCHE P06276 7/20 0.44
ACHE P22303 3/20 0.44
PIM1 P11309 1/20 0.41
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19151907 1.00 HDAC6 (0.54) HDAC6NOX1MEN1KMT2AADRA2A
SCHEMBL12190901 0.89 HDAC6 (0.62) HDAC6NOX1MEN1KMT2AADRA2A
SCHEMBL29851224 0.89 HDAC6 (0.62) HDAC6NOX1MEN1KMT2AADRA2A
SCHEMBL15470447 0.83 HDAC6 (0.57) HDAC6NOX1MEN1KMT2AADRA2A
SCHEMBL342426 0.83 HDAC6 (0.56) HDAC6NOX1MEN1KMT2AMAOA
SCHEMBL29387100 0.83 HDAC6 (0.56) HDAC6NOX1MEN1KMT2AMAOA
SCHEMBL4243905 0.80 HDAC6 (0.54) HDAC6NOX1MEN1KMT2AMAOA
SCHEMBL21915333 0.80 HDAC6 (0.58) HDAC6NOX1KMT2AADRA2AADRA2B
SCHEMBL8183708 0.80 HDAC6 (0.54) HDAC6NOX1KMT2AMAOABCHE
SCHEMBL1022593 0.80 HDAC6 (0.58) HDAC6NOX1MEN1KMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164992-A Diazaspiro [4.4] non-1, 3, 8-triene nitrile compound, and preparation method and application thereof 中山大学 2024-06-11 CN claimed
CN-112794985-B Transparent polyurethane optical material and preparation method thereof 温州大学新材料与产业技术研究院 2022-11-25 CN claimed
CN-118480063-A Heteropolycyclic aromatic hydrocarbon compound and organic electroluminescent device thereof 吉林省元合电子材料有限公司 2024-08-13 CN disclosed
CN-118164992-A Diazaspiro [4.4] non-1, 3, 8-triene nitrile compound, and preparation method and application thereof 中山大学 2024-06-11 CN disclosed
CN-112794985-B Transparent polyurethane optical material and preparation method thereof 温州大学新材料与产业技术研究院 2022-11-25 CN disclosed
CN-112794985-B Transparent polyurethane optical material and preparation method thereof 温州大学新材料与产业技术研究院 2022-11-25 CN disclosed