Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.62 |
| ▸ | PNP | P00491 | 1/20 | 0.57 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.55 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23392757 | 1.00 | TLR7 (0.62) | TLR7PNPTRAP1HSP90B1MTOR | |
| SCHEMBL23202316 | 0.89 | TRAP1 (0.69) | TLR7PNPTRAP1HSP90B1MTOR | |
| SCHEMBL30012102 | 0.89 | TRAP1 (0.69) | TLR7PNPTRAP1HSP90B1MTOR | |
| SCHEMBL23202278 | 0.88 | TLR7 (0.57) | TLR7PNPTRAP1HSP90B1MTOR | |
| SCHEMBL30011499 | 0.88 | TLR7 (0.57) | TLR7PNPTRAP1HSP90B1MTOR | |
| SCHEMBL18207505 | 0.81 | TLR7 (0.71) | TLR7PNPNUDT1 | |
| SCHEMBL23392983 | 0.79 | MTOR (0.55) | TLR7PNPTRAP1MTORALDH1A1 | |
| SCHEMBL30110559 | 0.79 | MTOR (0.55) | TLR7PNPTRAP1MTORALDH1A1 | |
| SCHEMBL18207625 | 0.78 | TLR7 (0.67) | TLR7PNPNUDT1 | |
| SCHEMBL21318950 | 0.77 | TLR7 (0.68) | TLR7PNPNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427063-A | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| EP-4065155-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |