Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.44 |
| ▸ | PDE4A | P27815 | 7/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30013176 | 0.81 | ADORA2A (0.64) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL30012879 | 0.79 | ADORA2A (0.47) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL30012788 | 0.75 | ADORA2B (0.43) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL31142181 | 0.75 | ADORA2B (0.47) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL31142206 | 0.74 | ADORA2A (0.47) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL31142176 | 0.73 | ADORA2B (0.41) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL31142182 | 0.73 | ADORA2B (0.45) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL30012368 | 0.71 | ADORA2A (0.43) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL30012331 | 0.71 | ADORA2B (0.65) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL31142180 | 0.69 | ADORA2A (0.41) | ADORA2AADORA2BPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065155-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |