Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27246243 | 1.00 | MGLL (0.54) | MGLLKCNH2GPR119USP2CYP3A4 | |
| SCHEMBL30013123 | 0.96 | MGLL (0.55) | MGLLKCNH2GPR119USP2CYP3A4 | |
| SCHEMBL27246255 | 0.88 | MGLL (0.55) | MGLLUSP2CYP3A4CYP2D6TSHR | |
| SCHEMBL30720224 | 0.88 | MGLL (0.55) | MGLLUSP2CYP3A4CYP2D6TSHR | |
| SCHEMBL30012082 | 0.87 | MGLL (0.54) | MGLLUSP2CYP3A4CYP2D6TSHR | |
| SCHEMBL27246221 | 0.87 | MGLL (0.54) | MGLLUSP2CYP3A4CYP2D6TSHR | |
| SCHEMBL27246300 | 0.84 | MGLL (0.54) | MGLLKCNH2GPR119USP2CYP3A4 | |
| SCHEMBL27246420 | 0.83 | MGLL (0.41) | MGLLKCNH2GPR119USP2CYP3A4 | |
| SCHEMBL30012893 | 0.83 | MGLL (0.41) | MGLLKCNH2GPR119USP2CYP3A4 | |
| SCHEMBL25326440 | 0.82 | MGLL (0.40) | MGLLKCNH2GPR119USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | claimed |
| EP-4326714-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-02-28 | — | — | EP | disclosed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |
| WO-2022223750-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-10-27 | — | — | WO | disclosed |