Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.42 |
| ▸ | MTOR | P42345 | 7/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23497520 | 0.78 | PIK3CA (0.43) | NPC1RAB9APIK3CAMTORPIK3R1 | |
| SCHEMBL6894445 | 0.77 | PIK3CA (0.50) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30013171 | 0.74 | PIK3CA (0.40) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL23497449 | 0.74 | PIK3CA (0.46) | RAB9AKDM4EMAPTPIK3CAMEN1 | |
| SCHEMBL23497499 | 0.74 | ALDH1A1 (0.40) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25140245 | 0.72 | CSNK1E (0.51) | KDM4EPIK3CDPIK3CBHPGD | |
| SCHEMBL30013825 | 0.72 | CSNK1E (0.51) | KDM4EPIK3CDPIK3CBHPGD | |
| SCHEMBL23508069 | 0.72 | MTOR (0.50) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL23497786 | 0.71 | PIK3CA (0.45) | KDM4EPIK3CAMTORPIK3R1ALDH1A1 | |
| SCHEMBL23508187 | 0.71 | PIK3CA (0.38) | KDM4EPIK3CAMTORPIK3R1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073072-A1 | PYRAZOLOTRIAZINES | Bayer Aktiengesellschaft (DE) | 2022-10-19 | — | — | EP | disclosed |