Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.48 |
| ▸ | PRKDC | P78527 | 5/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.48 |
| ▸ | SRC | P12931 | 4/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | HCK | P08631 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.48 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30013564 | 0.91 | BTK (0.52) | PIK3CDPIK3CGPRKDCPIK3CAPIK3CB | |
| SCHEMBL30013559 | 0.89 | PIK3CG (0.55) | PIK3CDPIK3CGPRKDCPIK3CAPIK3CB | |
| SCHEMBL30013434 | 0.85 | PIK3CG (0.52) | PIK3CDPIK3CGPRKDCPIK3CAPIK3CB | |
| SCHEMBL30013439 | 0.81 | PIK3CD (0.45) | PIK3CDPIK3CGPRKDCPIK3CAPIK3CB | |
| SCHEMBL27882603 | 0.81 | PIK3CD (0.71) | PIK3CDPIK3CGPRKDCPIK3CAPIK3CB | |
| SCHEMBL27900092 | 0.79 | PIK3CD (0.45) | PIK3CDPIK3CGPRKDCPIK3CAPIK3CB | |
| SCHEMBL30013557 | 0.78 | SRC (0.42) | PIK3CDPIK3CGPRKDCPIK3CAPIK3CB | |
| SCHEMBL27900223 | 0.74 | PIK3CD (0.49) | PIK3CDPIK3CGPRKDCPIK3CAPIK3CB | |
| SCHEMBL27900039 | 0.72 | PIK3C2B (0.53) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3C2B | |
| SCHEMBL131144 | 0.71 | PIK3CD (0.54) | PIK3CDPIK3CGPRKDCPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022171121-A1 | METHOD AND COMBINATION FOR TREATING TUMORS | 同润生物医药(上海)有限公司 | 2022-08-18 | — | — | WO | claimed |
| WO-2022171121-A1 | METHOD AND COMBINATION FOR TREATING TUMORS | 同润生物医药(上海)有限公司 | 2022-08-18 | — | — | WO | disclosed |