Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.50 |
| ▸ | JAK2 | O60674 | 19/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2598799 | 1.00 | NTRK1 (0.50) | NTRK1JAK2JAK1 | |
| SCHEMBL15154854 | 1.00 | NTRK1 (0.50) | NTRK1JAK2JAK1 | |
| SCHEMBL24168609 | 0.89 | NTRK1 (0.43) | NTRK1JAK2JAK1 | |
| SCHEMBL21587443 | 0.86 | NTRK1 (0.51) | NTRK1JAK2JAK1 | |
| SCHEMBL933690 | 0.85 | RIPK1 (0.44) | NTRK1JAK2 | |
| SCHEMBL23501031 | 0.85 | NTRK1 (0.49) | NTRK1JAK2JAK1 | |
| SCHEMBL933691 | 0.85 | RIPK1 (0.44) | NTRK1JAK2 | |
| SCHEMBL23501030 | 0.85 | NTRK1 (0.49) | NTRK1JAK2JAK1 | |
| SCHEMBL23070559 | 0.83 | NTRK1 (0.42) | NTRK1JAK2JAK1 | |
| SCHEMBL30152534 | 0.83 | NTRK1 (0.42) | NTRK1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3772516-B1 | TROPOMYOSIN RECEPTOR KINASE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | JIANGSU VCARE PHARMATECH CO LTD (CN) | 2022-12-14 | — | — | EP | disclosed |