Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 5/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202753 | 0.86 | MAPT (0.46) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL28176179 | 0.84 | KDM4E (0.44) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL14531754 | 0.84 | CYP4F2 (0.51) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL27938524 | 0.83 | FAAH (0.59) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL13091277 | 0.82 | SMN1; SMN2 (0.43) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL30939743 | 0.81 | FAAH (0.41) | POLBMAPTFAAHCYP4F2CYP4A11 | |
| SCHEMBL1997019 | 0.78 | CYP4F2 (0.46) | KMT2ACYP4F2CYP4A11 | |
| SCHEMBL28738828 | 0.78 | KDM4E (0.45) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL15763924 | 0.78 | CYP4F2 (0.45) | MEN1MAPTKMT2ACYP4F2CYP4A11 | |
| SCHEMBL16918662 | 0.76 | FAAH (0.60) | KDM4EMEN1POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076418-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |