Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30378145 | 0.89 | EGFR (1.00) | EGFR | |
| SCHEMBL21473613 | 0.89 | EGFR (1.00) | EGFR | |
| SCHEMBL30016823 | 0.86 | EGFR (0.87) | EGFR | |
| SCHEMBL28959187 | 0.86 | EGFR (0.87) | EGFR | |
| SCHEMBL30017106 | 0.86 | EGFR (0.79) | EGFR | |
| SCHEMBL14095984 | 0.86 | EGFR (0.89) | EGFR | |
| SCHEMBL30891807 | 0.86 | EGFR (0.89) | EGFR | |
| SCHEMBL21462325 | 0.84 | EGFR (0.83) | EGFR | |
| SCHEMBL30017178 | 0.82 | EGFR (0.80) | EGFR | |
| SCHEMBL30017520 | 0.82 | SRC (0.75) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403557-A | Quinoline and quinazoline compounds as fourth-generation EGFR (epidermal growth factor receptor) inhibitor and application thereof | 华东理工大学 | 2022-11-29 | — | — | CN | disclosed |