Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 17/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 17/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30017822 | 0.91 | GRIN1 (0.45) | GRIN1GRIN2BGRM2GRM5 | |
| SCHEMBL30017809 | 0.88 | CACNA1H (0.42) | GRIN1GRIN2BCACNA1H | |
| SCHEMBL30018361 | 0.83 | QPCT (0.47) | GRIN1GRIN2BCACNA1H | |
| SCHEMBL30017917 | 0.82 | GRIN2B (0.47) | GRIN1GRIN2BGRM2CACNA1H | |
| SCHEMBL30017771 | 0.81 | CACNA1H (0.41) | GRIN1GRIN2BCACNA1H | |
| SCHEMBL30103059 | 0.80 | KDM4E (0.40) | GRIN1GRIN2BGRM2CACNA1HGRM5 | |
| SCHEMBL24784624 | 0.79 | CACNA1H (0.39) | GRIN1GRIN2BGRM2CACNA1HGRM5 | |
| SCHEMBL30103038 | 0.79 | CACNA1H (0.39) | GRIN1GRIN2BGRM2CACNA1HGRM5 | |
| SCHEMBL24784623 | 0.77 | GRM5 (0.46) | GRIN1GRIN2BGRM5 | |
| SCHEMBL30103001 | 0.77 | GRM5 (0.46) | GRIN1GRIN2BGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257960-A1 | BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES | 武汉人福创新药物研发中心有限公司 | 2022-12-15 | — | — | WO | disclosed |