Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.45 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24784623 | 1.00 | GRM5 (0.46) | GRM5PDGFRBPDGFRANAAACYP1A2 | |
| SCHEMBL24784615 | 0.85 | GRM5 (0.46) | GRM5PDGFRBPDGFRANAAACYP1A2 | |
| SCHEMBL30103062 | 0.83 | KDM1A (0.49) | GRM5PDGFRBPDGFRAKDM1AFYN | |
| SCHEMBL24785826 | 0.83 | KDM1A (0.49) | GRM5PDGFRBPDGFRAKDM1AFYN | |
| SCHEMBL30018332 | 0.77 | GRIN1 (0.47) | GRM5GRIN1GRIN2B | |
| SCHEMBL9429978 | 0.74 | RAB9A (0.50) | PDGFRBPDGFRAKDM4EALDH1A1TDP1 | |
| SCHEMBL31128519 | 0.74 | PAX8 (0.46) | CYP1A2CYP3A4CYP2C19KDM4EALDH1A1 | |
| SCHEMBL31128539 | 0.74 | PAX8 (0.46) | CYP1A2CYP3A4CYP2C19KDM4EALDH1A1 | |
| SCHEMBL24667671 | 0.73 | PDGFRB (0.36) | PDGFRBPDGFRANAAACYP1A2CYP3A4 | |
| SCHEMBL30716893 | 0.73 | PDGFRB (0.36) | PDGFRBPDGFRANAAACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |