Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | MDM4 | O15151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30018939 | 0.93 | CASP3 (0.49) | CASP3MDM2TLR2MDM4TP53 | |
| SCHEMBL30069018 | 0.89 | PTPN1 (0.48) | CASP3MDM2 | |
| SCHEMBL29431036 | 0.89 | CASP3 (0.53) | CASP3MDM2TLR2MDM4TP53 | |
| SCHEMBL29462654 | 0.88 | CASP3 (0.55) | CASP3MDM2TLR2MDM4TP53 | |
| SCHEMBL29462951 | 0.87 | CASP3 (0.49) | CASP3MDM2TLR2MDM4TP53 | |
| SCHEMBL29706223 | 0.87 | CASP3 (0.52) | CASP3MDM2TLR2MDM4TP53 | |
| SCHEMBL29693009 | 0.87 | CASP3 (0.59) | CASP3MDM2MDM4TP53PIN1 | |
| SCHEMBL27172564 | 0.86 | PTPN1 (0.49) | MDM2 | |
| SCHEMBL27204705 | 0.86 | PTPN1 (0.49) | MDM2 | |
| SCHEMBL9437759 | 0.86 | MDM2 (0.57) | CASP3MDM2TLR2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337674-A2 | MODULATORS OF SORTILIN ACTIVITY | Insusense ApS (DK) | 2024-03-20 | — | — | EP | disclosed |
| EP-4326742-A1 | MODULATORS OF SORTILIN ACTIVITY | Insusense ApS (DK) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022238565-A2 | COMPOUNDS | INSUSENSE ApS (DK) | 2022-11-17 | — | — | WO | disclosed |
| WO-2022223805-A1 | MODULATORS OF SORTILIN ACTIVITY | INSUSENSE ApS (DK) | 2022-10-27 | — | — | WO | disclosed |