Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.62 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22595182 | 1.00 | EGFR (0.62) | EGFRINSRIGF1RALK | |
| SCHEMBL22595520 | 0.91 | EGFR (0.67) | EGFRINSRIGF1RALK | |
| SCHEMBL22595187 | 0.89 | EGFR (0.72) | EGFR | |
| SCHEMBL22596145 | 0.89 | EGFR (0.50) | EGFR | |
| SCHEMBL22595582 | 0.87 | EGFR (0.49) | EGFR | |
| SCHEMBL22596074 | 0.87 | EGFR (0.58) | EGFRINSRIGF1RALK | |
| SCHEMBL29559735 | 0.86 | EGFR (0.65) | EGFR | |
| SCHEMBL22595469 | 0.85 | EGFR (0.63) | EGFRINSRIGF1RALK | |
| SCHEMBL22595549 | 0.85 | EGFR (0.68) | EGFR | |
| SCHEMBL22595132 | 0.84 | EGFR (0.63) | EGFRINSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166103-B | EGFR inhibitor and application thereof | 江苏先声药业有限公司 | 2022-12-16 | — | — | CN | disclosed |