Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.58 |
| ▸ | INSR | P06213 | 5/20 | 0.52 |
| ▸ | IGF1R | P08069 | 5/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22595469 | 0.94 | EGFR (0.63) | EGFRINSRIGF1RALK | |
| SCHEMBL22595520 | 0.92 | EGFR (0.67) | EGFRINSRIGF1RALK | |
| SCHEMBL22595968 | 0.89 | EGFR (0.66) | EGFRINSRIGF1RALK | |
| SCHEMBL22595182 | 0.87 | EGFR (0.62) | EGFRINSRIGF1RALK | |
| SCHEMBL30018850 | 0.87 | EGFR (0.62) | EGFRINSRIGF1RALK | |
| SCHEMBL22595132 | 0.85 | EGFR (0.63) | EGFRINSRIGF1RALK | |
| SCHEMBL22596305 | 0.85 | EGFR (0.73) | EGFR | |
| Trifluoroacetic Acid SCHEMBL22587641 | 0.84 | EGFR (0.60) | EGFRINSRIGF1RALK | |
| SCHEMBL22595360 | 0.83 | EGFR (0.75) | EGFRINSRIGF1RALK | |
| SCHEMBL22595477 | 0.83 | EGFR (0.67) | EGFRINSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216371-A1 | EGFR INHIBITOR AND APPLICATION THEREOF | 江苏先声药业有限公司 | 2020-10-29 | — | — | WO | disclosed |