Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22588492 | 1.00 | EGFR (0.40) | EGFRMEN1KMT2AIGF1R | |
| SCHEMBL29747109 | 0.89 | EGFR (0.49) | EGFR | |
| SCHEMBL22025651 | 0.89 | EGFR (0.49) | EGFR | |
| SCHEMBL22595435 | 0.88 | EGFR (0.40) | EGFRMEN1KMT2AIGF1R | |
| SCHEMBL30018877 | 0.88 | EGFR (0.40) | EGFRMEN1KMT2AIGF1R | |
| SCHEMBL25641326 | 0.86 | EGFR (0.40) | EGFR | |
| SCHEMBL25056113 | 0.82 | ADRA2A (0.48) | EGFRMEN1KMT2AIGF1R | |
| SCHEMBL25642719 | 0.80 | MEN1 (0.42) | EGFRMEN1KMT2AIGF1R | |
| SCHEMBL31204432 | 0.80 | MEN1 (0.41) | EGFRMEN1KMT2AIGF1R | |
| SCHEMBL25056495 | 0.80 | MEN1 (0.41) | EGFRMEN1KMT2AIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166103-B | EGFR inhibitor and application thereof | 江苏先声药业有限公司 | 2022-12-16 | — | — | CN | disclosed |