Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.42 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666227 | 0.97 | ERAP2 (0.52) | ERAP2LNPEPFOLH1GNPATCYP3A4 | |
| SCHEMBL31167351 | 0.94 | ERAP2 (0.51) | ERAP2LNPEPFOLH1GNPATCYP3A4 | |
| SCHEMBL31754274 | 0.91 | FOLH1 (0.48) | FOLH1CYP3A4CYP2A6GPR132 | |
| SCHEMBL27041689 | 0.90 | FOLH1 (0.48) | FOLH1GNPATGPR132KISS1RECE1 | |
| SCHEMBL27041687 | 0.90 | FOLH1 (0.48) | FOLH1GNPATGPR132KISS1RECE1 | |
| SCHEMBL4198783 | 0.88 | GPR132 (0.52) | FOLH1GPR132KDM4EECE1 | |
| SCHEMBL31206620 | 0.87 | FNTA (0.47) | ERAP2LNPEPSLC15A2 | |
| SCHEMBL29395172 | 0.87 | ERAP2 (0.45) | ERAP2LNPEPFOLH1GNPATSLC15A2 | |
| SCHEMBL30641545 | 0.87 | FNTA (0.47) | ERAP2LNPEPSLC15A2 | |
| SCHEMBL29375944 | 0.87 | NAALAD2 (0.51) | FOLH1GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479587-B2 | Cationic intrinsically disordered antimicrobial peptides | CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) | 2022-10-25 | — | — | US | disclosed |