Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27347956 | 0.93 | HPGD (0.45) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL27307597 | 0.88 | CACNA2D1 (0.45) | KDM4EPKMHPGDRECQLACHE | |
| SCHEMBL24480292 | 0.86 | HPGD (0.46) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL27144706 | 0.86 | HPGD (0.57) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL412749 | 0.85 | HPGD (0.47) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL2386299 | 0.85 | CACNA2D1 (0.47) | HPGDRECQLEPHX1MAPTNR1H2 | |
| Trifluoroacetic Acid SCHEMBL27848432 | 0.83 | CACNA2D1 (0.45) | KDM4EPKMHPGDMAPTGPR119 | |
| SCHEMBL27162825 | 0.82 | KDM4E (0.42) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL24480620 | 0.81 | KDM4E (0.41) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL27314016 | 0.81 | KDM4E (0.41) | KDM4EPKMHPGDGPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326724-A1 | COMPOUND AS ADENOSINE A2A RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022224180-A1 | COMPOUND AS ADENOSINE A2A RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2022-10-27 | — | — | WO | disclosed |