Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 3/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL525225 | 0.93 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL165638 | 0.93 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL28668485 | 0.93 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL525223 | 0.93 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL3313118 | 0.93 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL10603415 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL11614722 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL809368 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Methane SCHEMBL7931585 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL11498883 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076521-B1 | SYNTHESIS OF SILYLSUBSTITUTED 1,2-ALKYNES | UNIV ADAM MICKIEWICZ (PL) | 2012-12-26 | — | — | EP | claimed |
| US-20090318726-A1 | NEW SILYLSUBSTITUTED 1,2-ALKYNES AND SYNTHESIS OF SILYLSUBSTITUTED 1,2-ALKYNES | ADAM MICKIEWICZ UNIVERSITY (PL) | 2009-12-24 | — | — | US | claimed |
| EP-2076521-A1 | NEW SILYLSUBSTITUTED 1,2-ALKYNES AND SYNTHESIS OF SILYLSUBSTITUTED 1,2-AIKYNES | Adam Mickiewicz University (PL) | 2009-07-08 | — | — | EP | claimed |
| WO-2008020774-A1 | NEW SILYLSUBSTITUTED 1,2-ALKYNES AND SYNTHESIS OF SILYLSUBSTITUTED 1,2-AIKYNES | ADAM MICKIEWICZ UNIVERSITY (PL) | 2008-02-21 | — | — | WO | claimed |
| EP-2076521-B1 | SYNTHESIS OF SILYLSUBSTITUTED 1,2-ALKYNES | UNIV ADAM MICKIEWICZ (PL) | 2012-12-26 | — | — | EP | disclosed |
| US-8293938-B2 | Alkylphosphonous acids, salts and esters, methods for the production thereof, and use of the same | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-10-23 | — | — | US | disclosed |
| US-20100190901-A1 | Alkylphosphonous Acids, Salts and Esters, Methods for the Production Thereof, and Use of the Same | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-07-29 | — | — | US | disclosed |
| US-20090318726-A1 | NEW SILYLSUBSTITUTED 1,2-ALKYNES AND SYNTHESIS OF SILYLSUBSTITUTED 1,2-ALKYNES | ADAM MICKIEWICZ UNIVERSITY (PL) | 2009-12-24 | — | — | US | disclosed |
| EP-2076521-A1 | NEW SILYLSUBSTITUTED 1,2-ALKYNES AND SYNTHESIS OF SILYLSUBSTITUTED 1,2-AIKYNES | Adam Mickiewicz University (PL) | 2009-07-08 | — | — | EP | disclosed |
| EP-1369422-B1 | PROCESS FOR PREPARATION OF ALKENYLPHOSPHINE OXIDES OR ALKENYLPHOSPHINIC ACID ESTERS | JAPAN SCIENCE & TECH AGENCY (JP) | 2008-07-23 | — | — | EP | disclosed |
| WO-2008020774-A1 | NEW SILYLSUBSTITUTED 1,2-ALKYNES AND SYNTHESIS OF SILYLSUBSTITUTED 1,2-AIKYNES | ADAM MICKIEWICZ UNIVERSITY (PL) | 2008-02-21 | — | — | WO | disclosed |
| US-7135583-B2 | Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20040059146-A1 | Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-03-25 | — | — | US | disclosed |
| EP-1369422-A1 | PROCESS FOR PREPARATION OF ALKENYLPHOSPHINE OXIDES OR ALKENYLPHOSPHINIC ACID ESTERS | Japan Science and Technology Corporation (JP) | 2003-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059146-A1 | Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters | PHOSPHO1, AGPS, AGPAT5 | TDP1 3773/4885CYP3A4 1357/4885ESR1 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.