Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.92 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.92 |
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28668485 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL165638 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL525223 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL3313118 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL11498883 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL5241027 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL10603415 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL809368 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Iodide SCHEMBL10825874 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Methane SCHEMBL7931585 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504566-B | Preparation method of bisacodyl | 广州市桐晖药业有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119708491-A | Polydisulfide polymer material containing hydroxy ester group and preparation method thereof | 衢州化工新材料创新研究院 | 2025-03-28 | — | — | CN | claimed |
| CN-119504566-A | Preparation method of bisacodyl | 广州市桐晖药业有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-115784847-B | New application of triphenylphosphine diiodide as reaction promoter | 南昌大学 | 2024-02-09 | — | — | CN | claimed |
| CN-115784847-A | New use of triphenylphosphine diiodide as reaction promoter | 南昌大学 | 2023-03-14 | — | — | CN | claimed |
| CN-113336717-A | Process for preparing oxazole carboxylic acid esters | 江西天新药业股份有限公司 | 2021-09-03 | — | — | CN | claimed |
| CN-102115540-B | Preparation method of alkali-resistant bisphenol A type unsaturated polyester resin | HUACHANG POLYMER CO LTD OF ECUST | 2014-12-03 | — | — | CN | claimed |
| US-8735629-B2 | Process for the reduction of a tertiary phosphine oxide to the corresponding tertiary phosphine in the presence of a catalyst and use of a tertiary phosphine for reducing a tertiary phosphine oxide in the presence of a catalyst | CHROMAFORA AB (SE) | 2014-05-27 | — | — | US | claimed |
| US-8461386-B2 | Hydrogenation of imines | UNITED PHOSPHORUS LIMITED (IN) | 2013-06-11 | — | — | US | claimed |
| CN-102115540-A | Preparation method of alkali-resistant bisphenol A type unsaturated polyester resin | HUACHANG POLYMER CO LTD OF ECUST | 2011-07-06 | — | — | CN | claimed |
| US-20110054217-A1 | HYDROGENATION OF IMINES | UNITED PHOSPHORUS LIMITED (IN) | 2011-03-03 | — | — | US | claimed |
| EP-2265373-A2 | HYDROGENATION OF IMINES | United Phosphorus Limited (IN) | 2010-12-29 | — | — | EP | claimed |
| WO-2009136409-A2 | HYDROGENATION OF IMINES | UNITED PHOSPHORUS LIMITED (IN) | 2009-11-12 | — | — | WO | claimed |
| JP-56059792-A | — | — | None | — | — | JP | disclosed |
| CN-119504566-B | Preparation method of bisacodyl | 广州市桐晖药业有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119504566-B | Preparation method of bisacodyl | 广州市桐晖药业有限公司 | 2025-04-25 | — | — | CN | disclosed |
| US-4188226-A | OXIDIZER, REDUCER, HALOGENATED CARBOCYCLIC COMPOUND | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-02-12 | — | — | US | disclosed |
| US-4173482-A | Dry image forming material containing an organic silver salt oxidizing agent, a reducing agent and a halogen molecule | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-11-06 | — | — | US | disclosed |
| US-4172832-A | Mercaptoalcohols and process for their manufacture | CIBA-GEIGY CORPORATION (US) | 1979-10-30 | — | — | US | disclosed |
| US-4070477-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054217-A1 | HYDROGENATION OF IMINES | KMO, HPD, HRH3 | ACHE 284/4885TDP1 2674/4885CYP3A4 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.