Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 7/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27248275 | 0.91 | TLR2 (0.52) | TLR2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL16328803 | 0.88 | TLR2 (0.59) | TLR2SIRT2KMT2ATLR1SIRT1 | |
| SCHEMBL15706395 | 0.86 | TLR2 (0.54) | TLR2SIRT2KMT2ATLR1MEN1 | |
| SCHEMBL15706348 | 0.86 | TLR2 (0.54) | TLR2SIRT2KMT2ATLR1MEN1 | |
| SCHEMBL15706322 | 0.86 | TLR2 (0.54) | TLR2SIRT2KMT2ATLR1MEN1 | |
| SCHEMBL12356377 | 0.86 | TLR2 (0.54) | TLR2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL14073721 | 0.85 | KMT2A (0.54) | TLR2SIRT2KMT2ATLR1 | |
| SCHEMBL14086305 | 0.85 | KMT2A (0.54) | TLR2SIRT2KMT2ATLR1 | |
| SCHEMBL27148382 | 0.85 | TLR2 (0.51) | TLR2SIRT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL31324458 | 0.85 | KMT2A (0.64) | TLR2SIRT2KMT2ATLR1SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326741-A1 | CYCLOPOLYPHOSPHAZENES, RELATED METHODS OF PREPARATION AND METHODS OF USE | University of Saskatchewan (CA) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022221959-A1 | CYCLOPOLYPHOSPHAZENES, RELATED METHODS OF PREPARATION AND METHODS OF USE | UNIVERSITY OF SASKATCHEWAN (CA) | 2022-10-27 | — | — | WO | disclosed |